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Cell Biology of Neurodegenerative Diseases 1.

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Prion diseases Prion disease: a new entity. Its significance in biomedical and basic research. Classification of prion diseases: human and animal forms.

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Brief characterization of scrapie, bovine spongiform encephalopathy BSEkuru and Creutzfeldt-Jakob disease. Infectivity, as a unique phenomenon. General overview of cell, tissue and organ culture systems: in vitro methods, their advantages and disadvantages, conditions and levels of their applications. The most important conditions and factors for in vitro survival, safety measures, the analyis and evaluation of the results, conclusion to in vivo processes.

Perfusion systems: in situ and isolated-perfused organ systems and organs, main types of arrangements constant flow-rate and pressure, single-pass and recirculation systemstechnical ground, perfusion fluids.

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Some examples of organ perfusion systems: liver, kidney, heart, pancreas. Organ cultures without perfusion.

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Embryonic and non-embryonic cultures, organitypic growth, solid, semisolid and liquid media, the problems of oxigenation, Developmental biology II An overview of body structure of the model organism World journal of diabetes predatory elegans. Handling and propagation of worms.

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Cell lineage, stages of embryonal and postembryonal development. Investigation of normal and developmental mutant worms Gametogenesis and localization of morphogens in the oocytes of Drosophila melanogaster. Determination of body axes and segments, introduction to stages of embryonal development.

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Anatomy of larvae, specificities of larval and imaginal tissues. Hormonal and genetic control of metamorphosis and organogenesis.

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Fertilization and embryonic develoment of zebrafish. An overview of molecular mechanisms that control fish development.

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Gingivitis cukorbetegség kezeléssel organs and larval development. Formation of the skull and adult organs. Pattern of morphogens in frog oocyte.

Europe SW Asia Fig. The sizes of grey circles are proportional to mtDNA-type frequency in the respective populations. Small uncoloured circles denote mtDNA types not found in the regional population.

Developmental genetics 1. Mutant analyis in nematodes C. Epistatic analysis in worms C. Double mutant analysis. Recessive epistatis, dominant epistasis, complementer inheritance, additive genetic interaction. Dissecting genetic pathways in C. Recessive epistasis.

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Analysis of the core apoptotic cell world journal of diabetes predatory pathway in C. Epistasis analysis. Analysis of the Gametogenesis: conversion of primordial germ cells into gametes. Mitosis, meiosis, polar bodies. Chromosomal abnormalities: 1.

2. típusú cukorbetegség mellitus kezelési szabványok

Oogenesis: maturation of oocytes before birth — primary oocytes, primordial follicles. Maturation of oocytes at puberty — primary, secondary and Graafian follicle.